Trisomia 8 (sindrome de warkany 2) reporte de dos casos

Abstract

Trisomy 8 is an uncommon anomaly in neonates, frequently being a lethal condition among individuals with pure trisomic
lines and more tolerable in mosaics cases. This aneuploidy is mainly characterized by a moderate - severe intellectual deficit
and poor motor coordination. Affected individuals presents craniofacial malformations, prominent forehead, arched palate,
deformed ears with low implantation, elongated trunk, reduced motility, articular defects and deep plantar grooves, which is
one of the main characteristics of this condition. Abnormalities of internal organs are of varying severity. We present the report
of two cases of trisomy 8 or Warkany syndrome 2 born at Instituto Nacional Materno Perinatal.