Variación de la beta-2 microglobulina en orina fetal en punciones sucesivas previo a derivación vesicoamniótica antenatal

Abstract

Introduction and objectives. Fetal obstructive uropathy can be treated early in pregnancy by intrauterine vesicoamniotic
shunting, immediately after being diagnosed by ultrasound, in specific cases with a favorable prognosis in renal function using
fetal urinary beta-2 microglobuline. The main objective of the study was to determine the changes of beta-2 microglobuline
in consecutive samples of fetal urine in 48 – 72 hour-intervals in fetuses with obstructive uropathy at 16 weeks of gestation.
Methods. We performed a descriptive and longitudinal study, including 15 pregnant women whose fetuses were diagnosed
with obstructive uropathy and without chromosomal abnormalities, performing vesicocentesis for urinary biometry.